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What causes Parkinson’s Disease?
The death of brain cells in the areas of the brain responsible for movement is what causes the development of Parkinson’s disease. The death of these cells are linked to an accumulation of proteins and plaques. The causes of what of the accumulation of these proteins and plaques are yet unknown says Dr Tabish Saifee, a Consultant Neurologist Queen Square.
Transcript
That's a very interesting question. We know that certain cells, again, primarily cells that are involved in the control of movement in the brain seem to get damaged and die off. And they're cells that are responsible for releasing dopamine for our everyday movements. These cells die off, not enough dopamine, and movements start to slow down and become stiffer. The reason these cells die is because of an accumulation of proteins, abnormal proteins in these cells which clump together and seem to be associated with damage to those cells.
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