This content is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Read more.
Marsden360
Marsden360
How does ctDNA liquid biopsy testing compare to traditional tissue biopsies?
Transcript
The great thing about the Marsden360 is it's a blood test, and there are
lots of patients who when they first present with advanced cancer,
may not be fit enough to have invasive tests. For example, some
patients who present with invasive lung cancer may not be well
enough to have a bronchoscopy and biopsy or a CT guided biopsy but
they're all well enough to have a blood test to get a diagnosis. And then
if you can get the diagnosis and find a molecularly matched treatment
and start them on it, most patients do extraordinarily well.
So, we have a scenario where we've gone from patients who historically might not have been able to get a diagnosis and certainly any treatment, to patients who immediately become treatable and have much better outcomes. So, it's much more patient friendly.
It's also much faster. If you have to go through a biopsy protocol, then you have to arrange the suitable biopsy, that might be a CT guided biopsy, it might be a bronchoscopy, it might be an ERCP.
If we take a blood test for the ctDNA, we reliably get the results back within five to ten days with the full molecular profile.
If you take a biopsy, firstly it goes to histopathology, histopathology look at it, they try and confirm that it's cancer, then they send it off for genomic testing and realistically you're looking at three to four weeks to get to the same point you can get in five to ten days with a blood test.
So, we have a scenario where we've gone from patients who historically might not have been able to get a diagnosis and certainly any treatment, to patients who immediately become treatable and have much better outcomes. So, it's much more patient friendly.
It's also much faster. If you have to go through a biopsy protocol, then you have to arrange the suitable biopsy, that might be a CT guided biopsy, it might be a bronchoscopy, it might be an ERCP.
If we take a blood test for the ctDNA, we reliably get the results back within five to ten days with the full molecular profile.
If you take a biopsy, firstly it goes to histopathology, histopathology look at it, they try and confirm that it's cancer, then they send it off for genomic testing and realistically you're looking at three to four weeks to get to the same point you can get in five to ten days with a blood test.